Non-Adherence to Antiretroviral Therapy and Factors Affecting Low Medication Adherence Among Incident HIV-Infected at Lerato Clinic in Germiston

Introduction: Highly active antiretroviral therapy (HAART) in the management of HIV/AIDS has made it possible to significantly reduce its incidence and morbidity mortality. The objective this study was identify factors affecting levels non-adherence HAART. Methods: investigator conducted a cross-sectional at Lerato Clinic Bertha Qxowa Hospital Germiston, Gauteng, South Africa from September 2019 December 2019. Were included participate, those being more than 18 years old, on HAART for least three months, consenting attending clinic that period. Non-adherence defined as taking their medication ≤ 95% time. A threshold >5% considered high, with P <0.05 statistically significant. Results: Of total 278 participants study, average age 41 ± 13 minimum 19 maximum 75 years, male predominance 56% (n ꞊ 156); 19% patients showed adherence 95%, which 13.31 (n=37) were men 5.4% (n=15). High blood pressure, hyperuricemia, hyperglycemia, LDL-hypercholesterolemia emerged clinico-biological determinants associated People who often found toxic/bad cared partners/spouses/parents risk non-adherence. Similarly, people busy doing other things "often" parent likely adhere Systolic pressure (SBP), uric acid, sugar, LDL cholesterol higher values. Conclusion: Effective requires <5% At end present individuals cardiometabolic. All these observations affirmed holistic multidisciplinary nature care.